Programme

P.38 -- Posters, VCTP-51

Date: Tuesday, 4 August 2026

Time: 09:30 - 10:30

Transition metal dichalcogenides heterostructures for lung cancer diagnosis via alveolar gas analysis

Ong Kim Le (1,2), Dang Long Quan (3), Pham Thanh Hai (4,5,6), Nguyen Luu Thanh Ngan (5,6), Nguyen Vu Dang Khoa (5,6), and Do Ngoc Son (5,6,*)

(1) Institute of Fundamental and Applied Sciences, Duy Tan University, Ho Chi Minh City, 70000, Vietnam; (2) Faculty of Natural Sciences, Duy Tan University, Da Nang City, 50000, Vietnam; (3) Department of Physics, College of Natural Sciences, Can Tho University; (4) Institute for Tropical Technology, 57A Truong Quoc Dung Street, Phu Nhuan Ward, Ho Chi Minh City 70000, Vietnam; (5) Ho Chi Minh City University of Technology (HCMUT), 268 Ly Thuong Kiet Street, Dien Hong Ward, Ho Chi Minh City, Vietnam; (6) Vietnam National University Ho Chi Minh City, Linh Xuan Ward, Ho Chi Minh City, Vietnam. * Email: dnson@hcmut.edu.vn

Early detection of lung cancer plays a decisive role in enhancing treatment efficacy and patient survival rates. Within this context, alveolar breath-sensing technology is recognized as a biomedical breakthrough, offering a non-invasive, safe, and highly cost-effective alternative to conventional clinical techniques. In this study, we design sensing films based on transition metal dichalcogenide heterostructures to precisely identify and screen volatile organic compounds acting as breath biomarkers. The primary advantage of these heterostructure systems over their pristine monolayer constituents lies in the formation of heterojunctions, which induce a robust built-in electric field that accelerates charge transfer kinetics upon interaction with target gas molecules. Utilizing density functional theory calculations, we elucidate the fundamental relationship between the geometric configurations, electronic structures, and gas-sensing characteristics of theses material systems. This work establishes a rigorous theoretical foundation, providing critical guidelines for the design, optimization, and fabrication of next-generation cancer-screening devices. Acknowledgement. This research was funded by Vietnam National University Ho Chi Minh City (VNU-HCM) under grant number A2025-20-02.

Presenter: Ong Kim Le