Trịnh Xuân Hoàng

Ph.D. in Physics, Institute of Physics, Polish Academy of Sciences, 2000
Magister & Engineer in Technical Physics, Warsaw University of Technology, 1996

Research interests

My studies mainly focus on understanding the behaviors of biomolecules and biomolecular systems by using theoretical, coarse-grained and all-atom models, computer simulation and statistical mechanics methods. My research problems include topics of protein folding, protein aggregation, protein-ligand interaction, and the formation of DNA condensates.

Our biophysics group

• Trinh Xuan Hoang (Institute of Physics, VAST), Ph.D.
• Nguyen Thi Thuy Nhung (Institute of Physics, VAST), Ph.D.
• Le Duy Manh (Ton Duc Thang University), Ph.D.
• Bui Phuong Thuy (Duy Tan University), Ph.D.
• Nguyen Ba Hung (Military Medical University), Ph.D.
• Le Hoang Phong (Institute of Physics, VAST), M.Sc.

Publications

Full list of publications

Group News

Apr 2025: Our study of lattice proteins in J. Chem. Phys. 162, 145104 (2025) suggests that solvation of peptide groups significantly contributes to folding cooperativity and the topology dependence of folding rates of two-state proteins.

Nov 2023: Our theoretical models and simulations in J. Chem. Phys. 158, 114904 (2023) indicate that DNA toroidal bundles are moderately twisted.

Feb 2020: Our work on a statistical mechanical model of biofouling appeared on the font cover of Biofouling (2018 impact factor 2.847), volume 36, issue 1.

Caption for the front cover image of Biofouling volume 36, issue 1, 2020 Examples of Ulva linza spore configuration for single (top left) and multiple spores on an unit cell of a Sharklet microtopographic surface. The spores of 5 mm in diameter are shown as filled purple circles. The Sharklet surface has four distinct features (yellow) of lengths equal to 4, 8, 12 and 16 mm, respectively. The feature width and the feature spacing are equal to 2 mm. The configurations are obtained by Monte Carlo simulations in the extended surface energetic attachment (SEA) model with spore-spore excluded volume interaction. The study shows that inter-organism interactions alter their attachment behaviors in high-density fouling. From Hoang TX, Mai HTH, Brennan AB, Le L. (2019). Effects of inter-organism interactions in biofouling on microtopographic surfaces. Biofouling 35(6): 684-695.