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Guide to Authors



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Submitting Manuscripts

 
Nature Genetics is an international monthly journal publishing exceptional advances in all fields of genetic research, with a special emphasis on genomics and mammalian genetics. Manuscripts are selected for publication according to editorial assessment of their general interest, suitability and reports from independent referees. Receipt of all manuscripts will be acknowledged. Contributors are welcome to suggest potential reviewers as well as informing the Editor of potential conflicts of interest. Authors must provide copies of related manuscripts under consideration by other journals.

Manuscripts should be submitted using our electronic submission website (http://www.nature.com/naturegenetics/esubmission/). Through this system authors can upload manuscript files (text, figures and video) directly to our editorial office. Authors can also check on the status of their manuscript while it is being considered. Additionally, reviewers can access the contents of a manuscript (in a highly secure manner) over a direct internet link thereby facilitating a rapid review process.

Alternatively, manuscripts, with the relevant computer disks may be sent to:

The Editor

Nature Genetics

345 Park Ave, 10th floor

New York, NY 10010-1707

Tel: 212 726 9314
 
 
Competing Financial Interests

 
In the interest of transparency, the Nature journals now require authors of research articles to declare any competing financial interests in relation to papers accepted for publication. For details, please see our
policy.
 
 
Manuscript Format

 
GENERAL FORMAT

 
Manuscripts should be typed, double-spaced and printed on one side of the paper only. An original and three copies are required, each accompanied by artwork. Reference lists, figure legends and tables should each be on separate sheets, also double-spaced. Please include four copies of any relevant manuscript in press or submitted for publication. Colour prints will be partly paid for by authors unless otherwise agreed. (Full details are available in our separate 'Style Guide'.)
 

Accessible language and clear expression.
Our primary concern is to facilitate communication of advances in genetic research in a clear and accessible fashion so that scientists across a broad range of disciplines will be able to appreciate their worth. It is in your interests to ensure that your manuscript is written in this manner throughout, paying especial attention to the abstract and first few paragraphs. Editorial suggestions from colleagues who do not necessarily have expertise in the immediate area of focus can be most helpful in this regard, and should be sought.
 
Nomenclature.
Proposed gene symbols must be registered with the appropriate nomenclature committee. Use our nomenclature guide at
http://genetics.nature.com/web_specials/nomen/ for live links to the URL of the appropriate nomenclature committee -- for example, the HUGO nomenclature committee and the mouse genome database. Check that other gene symbols are registered using the appropriate website database. Many symbols currently in popular use (for example, p53) are aliases; the correct gene symbol should be used at all times.
 
Materials.
As a condition of publication, authors are required to make materials and methods used freely available to academic researchers for their own use. Authors are required to state in the methods section any conditions for use of materials, and to provide full disclosure of the conditions on a freely accessible, identified web site.

This requirement includes antibodies and the constructs used to make transgenic animals, but not the animals themselves. Mutant strains of mice generated without the use of constructs must be submitted to a public repository at the time of publication, unless authors can ensure prompt distribution to academic researchers on request.

Papers reporting protein or DNA sequences and crystallographic structures will not be accepted without an accession number to GenBank/EMBL/DDBJ, Brookhaven, SWISS-PROT or other appropriate, identified, publicly available database in general use in the field that gives free access to researchers from the date of publication (see Nature 394, 105; 1998 and 404, 317; 2000). Accession numbers are provided directly to authors by these databases on deposition of data, and must be included in the Nature paper before publication. Microarray data should be made freely available to academic researchers on authors' own web sites or other freely available web site (the URL to be provided in the paper) until a public database is available.

Other supporting data sets must be made available to any interested reader on the publication date from the authors directly.

Researchers who encounter a persistent refusal by an author of a Nature paper to comply with these guidelines should contact the Editor of Nature Genetics, at natgen@natureny.com. (See Nature 416, 1; 2002 .)
 
Accession numbers.
Accession numbers should be provided in a separate section at the end of Methods, rather than in the text and figure legends.
 
Copyright.
In return for Nature Genetics' considering for publication the material you submit, you grant Nature Genetics an exclusive, irrevocable, royalty-free license to publish, reproduce, distribute, create derivative works from and otherwise use any such material ultimately accepted for publication, in any present or future medium worldwide. Nature Genetics shall have the right to edit such material as it sees fit.


 
ARTICLES

 
Articles include Abstract, Introduction, Results, Discussion and Methods sections. Titles should be simple and concise. A brief, accessible summary of no more than 100 words should explain the rationale and chief conclusions of the work, without references. The main text should be between 2,000 and 4,000 words in length. Results should include short cross-headings to define the main aspects of the study. The Methods section appears at the end of the text, before the Acknowledgements and References. Authors should deposit sequence data in the relevant database and provide accession numbers at the end of the Methods section. There is a maximum of eight display items. References are limited to 50, and are numbered sequentially as they appear in the text, followed by those in the figure legends and tables. Do not include any annotation. Full titles of papers are required. All authors should be listed unless there are six or more, in which case 'et al.' should be substituted after the first name. First and last page numbers must be included in full; references to books should also include editors, publisher, place and year of publication. The reference list should only include papers published or in press; web-site URLs, papers submitted or in preparation and personal communications should be cited in the text (citation of meeting abstracts is not permitted).
 
 
LETTERS

 
Nature Genetics also publishes a selection of more concise reports of broad interest to the genetics community. The main text (excluding legends, References and Methods) is limited to 1,200 words and four to six display items (tables and figures). There is no abstract; in its place, there is a single paragraph of up to 200 words, with references, containing the essential introductory material and culminating in a brief summary of the results. The remainder of the text is devoted to presenting the results and the principal conclusions of the work. There are no cross-headings. References are limited to 30 and should include full titles. Letters also contain a separate Methods section.
 
 
CORRESPONDENCE

 
Correspondence provides a venue for comment from the community. Nature Genetics seeks to promote discussion of issues relevant to genetic and genomic research and invites insightful, provocative and polemical correspondence. It also aims to provide its readers with information on useful and publicly available resources, descriptions of which will appear as Correspondences, subject to peer review. Correspondences are typically between 200 and 600 words in length (including figure legends) and can be cited in the normal fashion. They do not have summaries, abstracts or subtitles, and should contain no more than fifteen references (without titles) and two display items (either figures or tables).
 
 
BRIEF COMMUNICATIONS

 
Brief Communications are of broad and topical interest. They report peer-reviewed primary research, preliminary but intriguing advances on the current literature. Brief Communications are typically between 600 and 800 words in length, including legends, and include a short abstract of no more than 50 words. They can be cited in the normal fashion, are not divided into sections and have no more than fifteen references (without titles) and two display items (either figures or tables).
 
 
PROGRESSES & COMMENTARIES

 
Nature Genetics publishes a regular series of Progresses and Commentaries that are intended to be of general interest or utility to a broad section of our readership. Progresses provide an overview of the current 'state of affairs' in a specific area of genetic research. They should highlight recent advances and include predictions and/or recommendations for the future direction of research. Commentaries are essentially extended editorials that address particular issues relevant to the genetics community. They may, for example, focus on new research strategies, how resources are best utilized and the societal implications of genetic research.

Commentaries & Progresses are approximately 2,000-3,000 words in length with about 50 references. The article should begin with an abstract of 100-200 words summarizing the content and scope of the article. Concise subheadings should be used to introduce distinct sections and to navigate the reader through the article. The use of figures and cartoons is strongly encouraged; these can be used to illustrate a point, explain a concept, summarize research findings or simply for aesthetic appeal.

Nature Genetics welcomes submission of Commentary and Progress articles. Authors interested in contributing are encouraged to submit (by FAX or e-mail) a brief one-page synopsis outlining proposed content of the article. All Commentaries and Progresses are peer-reviewed.
 
 
SUBMISSION

 
All manuscripts should be submitted via our online manuscript tracking system (http://mts-ng.nature.com). If you need to send your manuscript to our editorial office, please address it to the Editor, Nature Genetics, 345 Park Avenue South, 10th Floor, New York New York 10010-1707, USA. Please provide current FAX and phone numbers of the corresponding author on all submissions. If you have any further questions, please contact our editorial department at (212) 726-9314; FAX (212) 545-8341; e-mail: natgen@natureny.com).
 
 
 
 
Nature Genetics Style Guide

 
 
ARTICLES

 
In the event that your manuscript is accepted for publication in Nature Genetics, it is our wish to see it published as soon as possible. This process may be expedited considerably if you assist us by presenting the final version of the text and figures in a form as close as possible to our house style. Your attention to these guidelines will help to ensure prompt and timely publication of your paper.
 

Title:
A succinct sentence of no more than 12 words. Avoid punctuation.
 
Authors:
Denote authors' affiliations with numerical superscripts (not symbols) preceding names. Give full details of authors' addresses; spell out US states in full and give full zip/post codes for the corresponding author. Please give authors' first names. The corresponding author is denoted as follows: 'Correspondence should be addressed to ... [initials].'
 
Summary:
No more than 100 words. It should contain a sentence of background information and preferably a concluding sentence as well.
 
Text:
Genes and loci should be denoted in italics. If referring to the protein product, however, use upright (Roman) text. References should be cited as superscripts (before punctuation), not in parentheses -- unless the reference follows a number, in which case parentheses should be used to avoid confusion. For example, 'chromosome 2 (refs 4-6)'. Multiple consecutive references are indicated with a hyphen. The results section should contain a series of short cross-headings of 4 to 8 words.
 
Methods:
Units should be specified (for example, 10 mg/ml). Ensure there is a space between numbers and units; for example, 2 mm. Names of manufacturers should be given in parentheses.
 
Acknowledgements:
Keep brief. Professional titles and affiliations are unnecessary. Grant numbers can be listed.
 
References:
There should be no more than 50 references.
  1. There should be one tab after the reference number and period.
  2. List author names with last name first. Six or more authors for one paper should be cited as first author followed by et al.
  3. No comma before or after et al. in any context. No comma before or after an ampersand (&).
  4. Include title of paper.
  5. Name of publication in italics.
  6. Volume number (bold) followed by comma.
  7. Page number range (use en dashes between numbers).
  8. Year of publication in parentheses.
  9. Reference MUST be at least 'in press' to be in the ref. list (otherwise, cite in text as 'manuscript in preparation/submitted', etc.).
  10. Journal abbreviations are as in Index Medicus.
Figures & Tables:
List figures as Fig. 1a, Fig. 2b et cetera. Do not capitalize or embolden heading. Figure panels are designated by lower-case italics. Do not use bold text. Figures and tables should have a brief title. There should be only ONE tab between each variable. Do not use any spaces to separate columns.
 
Proofs:
Within a few weeks of acceptance of your final manuscript, you will receive galley proofs for approval. The editor may have suggested certain areas that warrant updating or revising on the proofs; these can be accommodated with ease in the main text (and there is no charge for such corrections) although we do not encourage extensive rewriting. As editorial changes will have been made to ensure clarity and style, proofs should be examined very carefully. Corrected proofs should be faxed back to the Production Editor as soon as possible.

 
LETTERS

 
The Letters section of Nature Genetics presents concise reports of items of general interest to complement the articles it regularly publishes. The format for Letters is essentially the same as the familiar 'Letters to Nature'.
 
Heading:
As concise and informative as possible. Authors' affiliations are depicted with numerical superscripts. Please give authors' first names.
 
Main Text:
The total length of the main text (excluding figure legends and Methods) must be no more than 1,200 words. In place of the abstract, there should be a single paragraph of introductory material (no more than 200 words) with references, culminating in a brief summary of the results. The remainder of the text should be devoted to presenting the data and principal conclusions of the work. The discussion should be limited to a single, terse paragraph. There are no cross-headings.
 
Genes and loci should be denoted in italics. If referring to the protein product, however, use upright (Roman) text. References should be cited as superscripts (before punctuation), not in parentheses -- unless the reference follows a number, in which case parentheses should be used to avoid confusion. For example, 'chromosome 2 (refs 4-6)'. Multiple consecutive references are indicated with a hyphen.
 
Methods:
A concise description of methods (each starting with a short title) should be presented in a separate section entitled 'Methods'. Previously described methods should be cited without further description.
 
References:
There should be no more than 30 references with titles.
  1. There should be one tab after the reference number and period.
  2. List author names with last name first. Six or more authors for one paper should be cited as first author followed by et al.
  3. No comma before or after et al. in any context. No comma before or after an ampersand (&).
  4. Include title of paper.
  5. Name of publication in italics.
  6. Volume number (bold) followed by comma.
  7. Page number range.
  8. Year of publication in parentheses.
  9. Reference MUST be at least 'in the press' to be in the ref. list (otherwise, cite in text as 'manuscript in preparation/submitted', etc.).
  10. Journal abbreviations are as in Index Medicus.
Figures & Tables:
A maximum of six display items (tables and figures) is allowed. List figures as Fig. 1a, Fig. 2b et cetera. Do not capitalize or embolden heading. Figure panels are designated by lower-case italics. Tables should have a brief title. There should be only ONE tab between each variable. Do not use any spaces to separate columns.
 
Proofs:
Within a few weeks of acceptance of your final manuscript, you will receive galley proofs for approval. The editor may have suggested certain areas that warrant updating or revising on the proofs; these can be accommodated with ease in the main text (and there is no charge for such corrections) although we do not encourage extensive rewriting. As editorial changes will have been made to ensure clarity and style, proofs should be examined very carefully. Corrected proofs should be faxed back to the Production Editor as soon as possible.

Digital Figures Guide

 

Please indicate on submission whether artwork is available in digital format, but do not send digital files until your manuscript has been accepted.

When possible, we prefer to use original digital figures to ensure the highest quality reproduction in the journal. When creating and submitting digital files, please follow the guidelines below. Always send two sets of high quality printouts of your figures along with your accepted manuscript in the event that we cannot use your digital files.

| Formats | Resolution | Style | Sending files |
| FTP site | Hard copies | Color charges | Contact |

Formats

Resolution

Anything less than these standards will not reproduce well and will delay publication until we receive high resolution images or high quality printouts. We cannot be held responsible for assuming the cost of corrected reprints should poor quality images need to be used.

  • Color: 266 d.p.i. minimum; please convert all color files into CMYK mode
  • Grayscale: 600 d.p.i. minimum, such as blots and black & white photographs
  • Line art: 1200 d.p.i. minimum, such as graphs and illustrations

Please do not scan laser printouts of figures and send them to us as digital files. The dot pattern on a laser print often creates a moire pattern when scanned.

Style

Please give careful thought to clarity and layout, bearing in mind the final size of the printed page (170mm x 240mm). We try to size figures to approximately 1/4 of a page (85mm x 120mm), and only in unique situations do we publish figures much larger.

Please avoid the following:

Tables

Please avoid submitting tables in digital format as our tables follow a specific style guideline for consistency. Typeset your tables in a word processing document and amend the file to your text document.

Stereo Images

How to send files

Due to the possibility that we may have difficulties with your digital files, it is important to send them to Nature America as soon as your manuscript is accepted and finals edits have been made.

  • Floppy disk
  • Zip disk
  • Jaz disk
  • CD
  • SyQuest cartridge
  • FTP (see below)

FTP site

Using any type of FTP software, you can place files on our FTP site. Name your files with the corresponding author's name, figure number and letter, and file format (for example, Dr. Smith's figure 3a in TIFF format: smith3a.tiff). Do not use slashes (/,\) or hyphens (-) when naming your file. Please compress your files before uploading.

site address: ftp.nature.com
user name: genetics
password: natgen

Hard copies

Always submit two high quality printouts of your figures, original photograph (camera-ready) or glossy white paper preferred. Please follow same Style guidelines as above. Photocopies and poor laser printouts will not be accepted as they may produce moire patterns when printed.

Color charges

To help defray the cost of color printing, we charge for color figures, unless otherwise agreed. Please contact the Production Department for information and costs.

Contact If you have any further questions, please contact our Production Department at 212.726.9202; fax 212.696.9345; e-mail: i.mcnamara@natureny.com.

 
 
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