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MDL® Solid-Phase Organic Reactions

This database of reactions of small organic molecules on solid support is designed to meet the needs of combinatorial chemistry groups. The database includes extensive data on solid-phase organic chemistry, such as information on polymeric materials, linkers, solid supports, and protecting groups. The collection is selected, abstracted, and organized by FIZ CHEMIE Berlin.

Coverage:
1963-present (2,130 references); updated quarterly

Focus:
Coupling to and from solid support; insertion of linkers and spacers; functional group protection/deprotection; modification of solid-support functionalities

Source:
Original literature, 1963-present

Size:
13,300 reactions
20,100 molecules
updates add approx. 1,500 new reactions per year

Disk space:
182,000 VMS blocks (OpenVMS)
95 MB (AIX/IRIX/SOLARIS/NT)

Last Updated 24-Apr-2002

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