3rd International Workshop on Theoretical and
Computational Physics (IWTCP-3):
Complex Systems and Interdisciplinary Physics
Đà Lạt, 27-30 July 2015
in association with: 40th National Conference on Theoretical Physics

Program

I.6 -- Invited, IWTCP-3

Date: Tuesday, 28 July 2015

Time: 08h30 - 09h05

Energy transduction and dissipation in biomolecular motors and pumps

Gerhard Hummer

Department of Theoretical Biophysics, Max Planck Institute of Biophysics, 60438 Frankfurt am Main, Germany (Email: Gerhard.Hummer@biophys.mpg.de)

We have used molecular dynamics simulations and statistical mechanical theory to characterize the molecular mechanisms of biological energy transduction processes in the proton pumps cytochrome $c$ oxidase and complex I, and in the coupled rotary motors of F$_o$F$_1$-ATP synthase. These biomolecular machines efficiently interconvert chemical, electrostatic, and mechanical energy. Simulations and reduced physical models highlight their key mechanistic elements and shed light on the function of the bioenergetic machinery.

Presenter: Gerhard Hummer


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